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SomaFocus™

High-resolution electrophysiological readouts from inside intact 3D cultures

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Automated Platform

Automated Platform

Eliminate Extensive and Complicated Prep

SomaFocus uses complex software to automatically determine the optimal depth for recording inside intact organoids. Simply take an organoid from media, place it into our environmentally controlled platform and start recording instantly.

Semiconductor Technology

Semiconductor

Technology

 

The Core Technology

SomaFocus integrates our industry-leading silicon probe technology, trusted for decades in-vivo. Leveraging semiconductor-grade fabrication, the probes feature high-channel-count microelectrodes within a compact footprint, enabling high-density, parallel neural recordings. This precision engineering minimizes tissue disruption while maximizing the number of neurons measured in real time.

Real-Time Data Capture

AI-Driven, Real-Time
Data Capture

 

Live Circuit Readouts

SomaFocus captures live circuit-level activity from within brain organoids and other electrically active 3D cultures to reveal how neurons interact, communicate, and form circuits. Instantly view spiking activity, circuit synchrony, and network-level dynamics as recordings happen.

SomaFocus supports the discovery of organoid preclinical models for neurological disease research, bridging the gap between in-vitro experimentation and clinically relevant human neuroscience.
Make the Most of your 3D Model
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Assess Electrophysiological Function

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Disease Model for Drug Discovery

Real-time data captured as the probe advances through the organoid

Live Circuit Readouts from Deep Inside Intact Brain Organoids

SomaFocus captures live circuit-level activity from within brain organoids and other electrically active 3D cultures to reveal how neurons interact, communicate, and form circuits.

Real-Time Data Capture and Visualization

Instantly view spiking activity, circuit synchrony, and network-level dynamics from inside organoids as recordings happen. Analyze connectivity maps, oscillations, and excitatory/inhibitory balance across the 3D volume.

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Eliminate Extensive and Complicated Prep

Simply take an organoid from media, place it into our environmentally controlled platform and start recording instantly inside intact organoids. SomaFocus reveals the real-time functional dynamics of networks inside 3D tissues—not just their structure or molecular makeup.

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Collaborating with Leaders in Neuroscience — Join Us on the Path to Discovery
WHAT SCIENTISTS ARE SAYING:
I'm genuinely blown away by the SomaFocus system. We've tested several MEA platforms over the years and were never able to generate meaningful data from our organoid models, until now. SomaFocus has completely changed the game for us.
Andrea Rossi, PhD, Group Leader - Environmental Adaptation & Cellular ResilienceLabHead - Genome Engineering & Model Development Core Unit IUF-Leibniz Institute
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